Protecting People, Pets and Plants ™
Cis-capsaicin is used for the treatment of primary or recurrent herpes, as a topical analgesic used to treat osteoarthritis of the knee and other neuropathic pain. It is a tool used in neurobiological research.
Medicinal and Cosmetic
Cis-capsaicin is used in dermal patches, topical ointments, and creams to relieve minor aches and pains of muscles and joints. It has been reported that a single, hour-long application of a high-concentration capsaicin skin patch provided an average of 19 weeks of sustained reduction in the pain of neuralgia. In fact, one-eighth of the patients in a year-long multicenter, double-blind, randomized clinical trial of a dermal patch experienced such durable pain relief that they never required re-treatment. The others obtained a year of substantial pain relief with four 1-hour dermal applications of the capsaicin patch.
Concentrations are typically between 0.025% and 0.075%. Research suggests that capsaicin is able to kill prostate cancer cells. The studies showed tumors treated with capsaicin were about one-fifth the size of the untreated tumors. One study suggests capsaicin may be effective against lung cancer cells and researchers in Canada are testing capsaicin as a cure for diabetes.
Food and Beverage
Recently, capsaicin has been added to beverages to 'spice' them up.
Product Name: cis-Capsaicin
CAS No: 404-86-4
Specification: USP 30
Formula: C18 H27 NO3
|Appearance||White to Off White Powder|
|Odor||Very highly pungent and easily penetrating odor|
|Assay by HPLC||99.0% - 102.0%|
|Isometric Purity by HPLC (trans)||≥ 99.0% (area) trans-Capsaicin|
|Melting Point||64°C – 67°C|
|Loss on Drying||≤0.1%|
|Residue on Ignition||≤0.1%|
|Water, %, by KF||≤0.2%|
Solubility: Capsaicin in its pure state is poorly soluble in water but soluble in oil, chloroform, ethyl acetate